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XANAX
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Below is specific information on xanax:
Sedative-hypnotics are Central Nervous System (CNS) depressants and are a category of drugs that slow normal brain function. There are numerous CNS depressants; most act on the brain by affecting the neurotransmitter gamma-aminobutyric acid (GABA). Neurotransmitters are brain chemicals that facilitate communication between brain cells. GABA works by decreasing brain activity. Although the different classes of CNS depressants work in unique ways, ultimately it is through their ability to increase GABA activity that they produce a drowsy or calming effect that is beneficial to those suffering from anxiety or sleep disorders.
Among the medications that are commonly prescribed for these purposes are the following:
- Barbiturates, such as mephobarbital (Mebaral) and pentobarbital sodium (Nembutal), which are used to treat anxiety, tension, and sleep disorders.
- Benzodiazepines, such as diazepam (Valium), chlordiazepoxide HCl (Librium), and alprazolam (Xanax), which can be prescribed to treat anxiety, acute stress reactions, and panic attacks; the more sedating benzodiazepines, such as triazolam (Halcion) and estazolam (ProSom) can be prescribed for short-term treatment of sleep disorders.
In higher doses, some CNS depressants can be used as general anesthetics.
Despite their many beneficial effects, barbiturates and benzodiazepines (Xanax) have the potential for abuse and should be used only as prescribed. During the first few days of taking a prescribed CNS depressant, a person usually feels sleepy and uncoordinated, but as the body becomes accustomed to the effects of the drug, these feelings begin to disappear. If one uses these drugs long term, the body will develop tolerance for the drugs, and larger doses will be needed to achieve the same initial effects. In addition, continued use can lead to physical dependence and - when use is reduced or stopped - withdrawal.
Because all CNS depressants work by slowing the brain's activity, when an individual stops taking them, the brain's activity can rebound and race out of control, possibly leading to seizures and other harmful consequences. Although withdrawal from benzodiazepines can be problematic, it is rarely life threatening, whereas withdrawal from prolonged use of other CNS depressants can have life-threatening complications. Therefore, someone who is thinking about discontinuing CNS depressant therapy or who is suffering withdrawal from a CNS depressant should speak with a physician or seek medical treatment.
Side-Effects
- Anaemia, impairment of liver function, chronic intoxication (headache, impaired vision, slurred speech) and depression. Babies of chronic users may have difficulty in breathing and feeding, disturbed sleep patterns, sweating, irritability and fever.
- CNS depressants should be used with other medications only under a physician's supervision. Typically, they should not be combined with any other medication or substance that causes CNS depression, including prescription pain medicines, some over-the-counter cold and allergy medications, or alcohol. Using CNS depressants with these other substances - particularly alcohol - can slow breathing, or slow both the heart and respiration, and possibly lead to death. It is very important to get the use of this drug stopped. One of the ways to do that is to do regular urine drug testing of the person who is using this drug.
Health Hazards
- Anaemia, impairment of liver function, chronic intoxication (headache, impaired vision, slurred speech) and depression. Babies of chronic users may have difficulty in breathing and feeding, disturbed sleep patterns, sweating, irritability and fever.
- Very significant levels of physiological dependence marked by both tolerance and withdrawal, can develop to the sedatives, hypnotics and anxiolytics. The timing and severity of the withdrawal syndrome will differ depending on the specific substance and its pharmacokinetics and pharmacodynamics.
Symptoms
- Symptoms of dependence - tolerance resulting in higher levels needed to achieve the same calming effect.
- Symptoms of psychological dependence - needing the drug to function and being consumed with obtaining the drug.
- Symptoms of withdrawal - restlessness, insomnia, anxiety, seizures, even death in some cases.
To be clinically diagnosed as dependent on a substance, 3 or more of the following symptoms must be exhibited at the same time during a 12-month period:
- Amount and duration of substance intake is longer than intended
- Efforts to control substance intake are not successful
- A great deal of effort is put into obtaining, using or recovering from effects of the substance in question
- Due to use of substance, other activities (social, work-related, leisure) are reduced or abandoned
- Substance is used even when know to cause or exacerbate a persistent or recurrent psychological, or physical problem
- Tolerance of the substance
- Withdrawal from the substance
More Information
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