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Percodan, Endodan, Percodan-Demi, Roxiprin

What Is It?

Percodan is a potent opioid painkiller used to treat moderately/severe but short-term pain.

Prior to Tylenol, Percodan was the main oral pain treatment due to the potency. Percodan has now largely been replaced by Percocet.

Percodan originally contained a small amount of caffeine.

The usual adult dosage of Percodan is one tablet every 6 hours or as needed for pain, not to exceed 12 tablets in 24 hours.


As all products containing oxycodone have the potential to be habit-forming, Percodan is no exception.

Percodan is subject to the Federal Controlled Substances Act (Schedule II); it was a favorite of and eagerly sought after by opiate addicts.

Many opiate addicts now prefer OxyContin. Percodan and Percocet each contain aspirin and Tylenol, respectively and OxyContin does not contain any other active ingredients besides oxycodone.